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PURPOSE: To estimate the frequencies of dicentric chromosomes in peripheral lymphocytes of astronauts on missions to Mars. MATERIALS AND METHODS: Calculations of expected frequencies of dicentrics are based on dose estimations and lymphocyte biology. RESULTS: Frequencies of dicentrics are predicted to be 10-40 times higher than the background level. CONCLUSIONS: Stressing the importance of careful mission planning and optimized shielding of transfer vehicle to Mars.
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G. Obe (1999) studied this question.
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