Key result
The mini-extracorporeal system resulted in significantly higher postoperative platelet and procalcitonin values compared to the conventional method in patients undergoing coronary bypass surgery.
Why the study?
The study was conducted to compare platelet activation in patients undergoing coronary bypass surgery with conventional versus mini extracorporeal systems.
Does the mini-extracorporeal system improve platelet activation compared to conventional extracorporeal systems in patients undergoing coronary bypass surgery?
Cohort (n=116)
Does the mini-extracorporeal system improve platelet activation compared to conventional extracorporeal systems in patients undergoing coronary bypass surgery?
The mini-extracorporeal system may offer more favorable postoperative platelet and procalcitonin profiles compared to conventional systems in coronary bypass surgery.
These lab differences should not yet alter perfusion choices in CABG; hypothesis-generating for clinical outcomes in prospective trials.
Aim: The aim of this study was to compare platelet activation in patients undergoing coronary bypass surgery with conventional and mini extracorporeal systems. Material and Methods: Our study is a retrospective study and a total of 116 patient data were obtained. Patients were divided into two groups as conventional extracorporeal and mini extracorporeal system bypass patients. Equal numbers of patients (n=58) were included in both groups. The data of patients who underwent coronary bypass surgery with conventional and mini extracorporeal systems between January 2022 and December 2022 were included in the study. Results: In our study, no significant difference was found between patients bypassed with conventional and mini extracorporeal system in terms of pump time and cross-clamp time. Although the duration of intensive care unit stay and total hospitalization were found to be shorter in patients bypassed with the mini-extracorporeal (MECC) system than those bypassed with the conventional method, the difference between the groups was not significant. As a result of our study, it was observed that postoperative ejection fraction (EF) values significantly increased and hematocrite (HTC), hemoglobin (Hb), platelet (PLT) and procalcitonin (PCT) values significantly decreased in both groups of patients who underwent bypass with conventional and MECC system, and no significant difference was found between pre- and postoperative mean platelet volume (MPV) and platelet distribution width (PDW) values. As a result of our study, postoperative PLT and PCT values in the MECC group were found to be significantly higher than those in patients who underwent bypass with the conventional method. Conclusion: Considering the results obtained in our study, it is seen that the values in patients bypassed with the MECC system are more favorable than those bypassed with the standard method, but more studies on the subject are needed.
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Uzum et al. (2024) conducted a cohort in Coronary bypass surgery (n=116). Mini extracorporeal system (MECC) vs. Conventional extracorporeal system was evaluated on Platelet activation (PLT, PCT, MPV, PDW). The mini-extracorporeal system resulted in significantly higher postoperative platelet and procalcitonin values compared to the conventional method in patients undergoing coronary bypass surgery.
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