Population
Rat anterior pituitary gonadotrophs
Design
Preclinical
Follow-up
1-30 minutes
Authors
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Animal data on pituitary ANP handling warrant caution against clinical extrapolation; leaves open autocrine/paracrine roles in human gonadotrophs.
Rat anterior pituitary gonadotrophs can both synthesize and internalize extracellular ANP, suggesting autocrine and paracrine actions in the anterior pituitary gland.
Morel et al. (1989) studied this question.
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