Key result
A 40-year-old man with rheumatoid arthritis developed Salmonella septic arthritis while on certolizumab, which was successfully detected by ultrasound and treated with antibiotics.
Case Report (n=1)
This case highlights the possibility of Salmonella septic arthritis in rheumatoid arthritis patients treated with certolizumab, detectable by ultrasound.
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May heighten suspicion for Salmonella septic arthritis in certolizumab-treated RA; case report leaves open need for prospective validation.
We report a case of Salmonella septic arthritis detected by ultrasound in a 40-year-old man with rheumatoid arthritis while he was on anti-tumor necrosis factor-α monoclonal antibody certolizumab. An aspirate of his left elbow joint showed Salmonella enteritidis infection that was sensitive to ceftraixone. This was preceded by a brief episode of loose stools following a visit to the Far East. He was treated with antibiotics and made a good recovery. There have only been a few case reports of Salmonella septic arthritis in a rheumatoid arthritis patient on anti-tumor necrosis factor treatment but none previously in association with certolizumab.
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Nandagudi et al. (2014) conducted a case report in Rheumatoid arthritis and Salmonella septic arthritis (n=1). Certolizumab was evaluated on Detection and treatment of Salmonella septic arthritis. A 40-year-old man with rheumatoid arthritis developed Salmonella septic arthritis while on certolizumab, which was successfully detected by ultrasound and treated with antibiotics.
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