Key result
Bayesian methods using a Markov chain prior distribution were proposed to restore the underlying quantal signal from noisy single-channel patch clamp recordings.
Population
Single-channel patch clamp recordings of cell membrane ion channels
Design
Other
Authors
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May aid ion channel research analysis; leaves open empirical validation before adoption.
This methodological paper introduces a Bayesian approach to filter noise and restore quantal signals in single-channel patch clamp recordings.
D. R. Fredkin (1992) studied this question. Bayesian restoration methods using Markov chain prior distribution was evaluated on Restoration of underlying quantal signal from noisy measurements. Bayesian methods using a Markov chain prior distribution were proposed to restore the underlying quantal signal from noisy single-channel patch clamp recordings.
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