Effect of Bilateral Nephrectomy and Kidney Transplantation on Hypertension in Man

In conclusion, we consider that renal hypertension may have two components: a renal component and a renoprival component (fig. 6). Bilateral nephrectomy abolishes the renal component and leaves a renoprival hypertension that is sensitive to water and salt. Implantation of a kidney may cure the renoprival hypertension. Rejection of the graft may then be followed by a return of renal hypertension. Since the technique of transplantation of kidneys taken from cadavers is improving steadily, repeated nephrectomies and a second transplant become possible.