Why the study?
Does serum angiotensin-converting enzyme (SACE) level help differentiate sarcoidosis from non-sarcoid uveitis?
Does serum angiotensin-converting enzyme (SACE) level help differentiate sarcoidosis from non-sarcoid uveitis?
Elevated serum angiotensin-converting enzyme is closely linked to sarcoidosis and may be a valuable diagnostic tool for evaluating patients with uveitis for a sarcoid origin.
Elevated SACE may support sarcoid uveitis diagnosis; leaves open prospective validation before routine use.
Serum angiotensin-converting enzyme (SACE) was studied in a group of 29 sarcoidosis patients (among whom five had uveitis) and in 22 patients with non-sarcoid uveitis. SACE was normal in all non-sarcoid patients and elevated in 62 per cent of the patients with sarcoidosis. Thus an elevated SACE is closely linked to sarcoidosis and may be a valuable tool in evaluating patients with uveitis in search of a sarcoid origin.
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Rømer et al. (1980) studied this question.
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