Key result
The percentage of time in pre-burst suppression was inversely associated with preoperative cognitive function (β -0.04, p=0.009) but not with postoperative delirium (OR 1.04, p=0.421).
Why the study?
Intraoperative burst suppression has modest sensitivity for predicting postoperative delirium, prompting evaluation of whether preceding transient reductions in EEG power (pre-burst suppression) occur and associate with preoperative cognitive function and delirium risk.
Population
83 patients ≥age 60 scheduled for ≥2-h non-cardiac, non-neurologic surgery under general anesthesia
Comparison
Percentage of time in preBSup vs preoperative cognitive function, BSup time, and POD incidence
Design
Analysis of data from 2 prospective cohort studies
Authors
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Pre-burst suppression may mark preoperative cognitive status on EEG; hypothesis-generating and should not yet change perioperative monitoring.
Cohort (n=83)
Yes
Odds Ratio: 1.04 (95% CI 0.95–1.14)
p-value: p=0.421
Pre-burst suppression on intraoperative EEG is inversely associated with preoperative cognitive function in older adults, though not significantly predictive of postoperative delirium.
Reese et al. (2023) conducted a cohort in Postoperative delirium (POD) and preoperative cognitive impairment (n=83). Pre-burst suppression (preBSup) on EEG was evaluated on Postoperative delirium (POD) incidence (OR 1.04, 95% CI 0.95, 1.14, p=0.421). The percentage of time in pre-burst suppression was inversely associated with preoperative cognitive function (β -0.04, p=0.009) but not with postoperative delirium (OR 1.04, p=0.421).
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