Key result
The etiology of postoperative cognitive dysfunction remains unclear, but factors such as age, education level, health status, and potentially neurotoxic anesthetics may contribute to its development.
Why the study?
Elderly patients with comorbidities undergoing surgery are prone to cognitive disorders termed postoperative cognitive dysfunction, yet its etiology remains unclear and unproven.
Comprehensive preoperative assessment and careful perioperative pharmacological management are needed to mitigate the risk of postoperative cognitive dysfunction in elderly patients.
POCD etiology remains incompletely defined despite candidate risks; leaves open prospective studies to establish causality and prevention.
Along with ages, elderly patients with comorbid who undergoing surgicalprocedures are more likely to experience cognitive disorders such as decreasedquality of life and loss of independence. This is known as postoperative cognitivedysfunction. The percentage is quite significant for old age to experience cognitivedisorders. Ages, education level, health and mental status can be a factor causingcognitive disorders. Comprehensive assessment of objective mental, social andfunctional status can increase patient preoperative. Perioperativepharmacological management can reduce the incidence of POCD. For example,minimal use of propofol in spinal anesthesia may reduce POCD in hip fracturesurgery. The use of dexmedetomidine in ventilated patients in the ICU may alsoreduce POCD. The etiology is still unclear, but there is a suspicion that the useof neurotoxic anesthetics can trigger the occurrence of POCD, but this has notbeen further proven.
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Irfan Ferdinand Tambunan (2021) conducted a review in Post Operative Cognitive Dysfunction. Anesthesia and Surgery was evaluated. The etiology of postoperative cognitive dysfunction remains unclear, but factors such as age, education level, health status, and potentially neurotoxic anesthetics may contribute to its development.
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