Fluorescent silica nanotubes are synthesized through a sol–gel reaction using an anodic aluminum oxide membrane template. The nanotubes are filled with plasmid DNA encoding green fluorescence protein (GFP), which are incorporated into mammalian cells that subsequently express GFP (see Figure). The results demonstrate a novel application of nanotubes in biomolecule delivery.
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Chen et al. (2005) studied this question.
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