Key result
Surgical management of coarctation of the aorta, including subclavian flap angioplasty and prostaglandin E1 stabilization, is safe and desirable in infancy to minimize late cardiovascular morbidity.
Surgical repair of coarctation of the aorta in infancy is safe and desirable to minimize late cardiovascular morbidity and premature death associated with hypertension.
Supports early infant repair to limit late morbidity; leaves open need for prospective validation.
Progress in the management of coarctation of the aorta over the past 40 years is truly impressive. Nonoperative management of this condition has uniformly met with failure; however, a variety of surgical options is now available for the treatment of children and adults with coarctation. In recent years, significant advances have emerged in the treatment of neonates and infants that have resulted in low operative mortality rates. In addition, our own results with the subclavian flap angioplasty in these young patients indicate that the problem of failure of the repaired area to grow has been all but eliminated. The use of prostaglandin E1 has dramatically improved our ability to stabilize the decompensated neonate. Repair of coarctation in infancy is not only safe but desirable to minimize the late cardiovascular morbidity and premature death associated with hypertension.
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Campbell et al. (1985) conducted a review in Coarctation of the aorta. Surgical management (including subclavian flap angioplasty) and prostaglandin E1 vs. Nonoperative management was evaluated. Surgical management of coarctation of the aorta, including subclavian flap angioplasty and prostaglandin E1 stabilization, is safe and desirable in infancy to minimize late cardiovascular morbidity.
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