Key result
Endovascular repair of abdominal aortic aneurysms resulted in significantly lower long-term survival compared to an age-matched population (P < 0.0001).
Why the study?
Does EVAR provide long-term survival equivalent to an age-matched population in patients with abdominal aortic aneurysms?
Cohort (n=145)
No
Does EVAR provide long-term survival equivalent to an age-matched population in patients with abdominal aortic aneurysms?
p-value: p=<0.0001
While EVAR for abdominal aortic aneurysms has acceptable 30-day mortality, it may not restore long-term survival to that of an age-matched population, highlighting the importance of careful patient selection.
May warrant stricter EVAR selection; leaves open whether adjunctive strategies can close the survival gap.
Purpose: To investigate the long term survival benefit for the treatment of abdominal aortic aneurysmal (AAA) disease with Endovascular Aneurysm Repair (EVAR). Our hypothesis is that patients undergoing EVAR have an equivalent survival to an age matched population. Methods: Between 1997 and 2014 all patients treated for an AAA with EVAR by a single surgeon were prospectively followed and at 12 monthly intervals ultrasonography was utilised to assess the size of the aorta after treatment. Data from the Births, Deaths and Marriages was also collected regarding the survival of these patients. As of 2003 all patients with AAA were treated electively with EVAR. Results: There were a total of 145 patients treated with EVAR for AAA during the study period, 143 who survived the 30-day post-operative period. The long-term survival following EVAR at one year was 95% (95% C.I.: 88% to 97%), at 5 years 56% (95% C.I.: 42% to 64%), and at 10 years 28% (95% C.I.: 17% to 42%). Compared to an age-matched population the EVAR group had a lower than expected long term survival (P < 0.0001). Discussion: EVAR for the treatment of abdominal aortic aneurysms can be achieved with acceptable 30 day survival and freedom from aneurysm related death. However selection of patients for EVAR may significantly effect long-term survival if patients are fit for EVAR but not open operation. The question arises as to whether EVAR should be performed in patients with questionable long-term survival, even if they are fit for this procedure.
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Englund et al. (2016) conducted a cohort in Abdominal Aortic Aneurysm (n=145). Endovascular Aneurysm Repair (EVAR) vs. Age-matched population was evaluated on Long-term survival (p=<0.0001). Endovascular repair of abdominal aortic aneurysms resulted in significantly lower long-term survival compared to an age-matched population (P < 0.0001).
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