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Does simultaneous great cardiac vein and coronary sinus blood sampling detect regional differences in flow and metabolism in the canine left ventricle?
Does simultaneous great cardiac vein and coronary sinus blood sampling detect regional differences in flow and metabolism in the canine left ventricle?
Simultaneous great cardiac vein and coronary sinus blood sampling can detect regional differences in myocardial flow and metabolism in a canine model.
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GCV/CS sampling yields comparable flow and metabolic indices in normal canine ventricles; leaves open detection of regional differences in disease models.
tion of regional myocardial perfusion and ischemiu from coronary venous blood. Am. J. Physiol. 236(2): H385-H390, 1979 or Am. J. Physiol.: Heart Circ. Physiol. 5(2): H385-H390, 1979.-The usefblness of simultaneous great cardiac vein (GCV) and coronary sinus (CS) blood sampling for detecting regional differences in flow per unit weight (F/W) and metab-olism has been examined in the canine left ventricle. In normally perfused ventricles, F / Ws in myocardium repre-sented in GCV and CS drainage agreed within 210 % over a wide range (23-355 (ml/min)/lOOg); GCV and CS Pcoz, pH, and percent lactate extraction differed by 0.45 2 1.5 (SD) mmHg, 0.002 t 0.014 units, and 0.3 t 5.4%, respectively. GCV F/W exceeded CS F/W by X0 % during selective in-creases in left anterior descending (LAD) inflow or reductions in left circumflex (LC) inflow; it was X0 % below CS F/W
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Roberts et al. (1979) studied this question.
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