What does this research mean for the field?

Great cardiac vein blood is remarkably free of left circumflex arterial inflow across both normal and abnormal physiological states, whereas the origin of mid-coronary sinus blood is highly variable. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

February 1, 1976American Journal of Physiology-Legacy Content

Origin of great cardiac vein and coronary sinus drainage within the left ventricle

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Structured PICO

Population

Open-chest dogs

Intervention

Infusion of dissolved helium (He) and hydrogen (H2) into external circuits perfusing the left anterior descending (LAD) and left circumflex (LC) arteries, respectively, with alterations of preload, afterload, and selective LAD or LC obstruction and vasodilation

Comparator

Basal conditions

Outcome

Steady-state concentrations of He and H2 measured chromatographically at various points within the great cardiac vein (GCV) and coronary sinus (CS)surrogate

This study demonstrates that great cardiac vein blood is remarkably free of left circumflex inflow in both normal and abnormal physiological states in dogs.

Discussion

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Implication

Supports GCV sampling for LAD-specific assessment in canine models; leaves open human translation.

Cite This Study

Roberts et al. (1976) studied this question.

synapsesocial.com/papers/6a19328aa0353395e957ff98 https://doi.org/10.1152/ajplegacy.1976.230.2.486

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Origin of great cardiac vein and coronary sinus drainage within the left ventricle

Structured PICO

Discussion

Implication

Cite This Study

Origin of great cardiac vein and coronary sinus drainage within the left ventricle

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider