Key result
Systemic lupus erythematosus was associated with a 30.5% prevalence of metabolic syndrome compared to 20.5% in controls, which was not statistically significant (p=0.117).
Why the study?
Does systemic lupus erythematosus and its specific factors (SLICC criteria) predict the presence of metabolic syndrome in women?
Cross-Sectional (n=59)
Does systemic lupus erythematosus and its specific factors (SLICC criteria) predict the presence of metabolic syndrome in women?
Answers are grounded in this paper and cite their sources.
In this pilot study, despite a numerically higher prevalence of metabolic syndrome in women with SLE compared to controls, the association was not statistically significant, nor were SLE-specific factors predictive of MetS.
As with mostprevious studies on the prevalence of metabolicsyndrome (MetS) in systemic lupus erythematosus(SLE), in which the prevalence varies greatly, itwas found to be always greater than in non-lupus patients. MetS, a bundle of cardiovascular risk factors, is highly prevalent and associated with increased rate of cardiovascular events and death. Apart from these risk factors, MetS is closely correlated with inflammation. Not only are they related to each other, but the inflammatory burst also precedes the MetS. Was evaluated the influence of SLICC criteria and other disease-specific factors in the presentation of MetS. In order to evaluate these factors, It was conducted a cross-sectional pilot study with 59 women with SLE according to the American College Rheumatology (ACR) criteria at the rheumatology out patient clinic. Individuals with SLE had a higher prevalence of MetS (30.5%) than controls (20.5%), as shown previously. Despite this higher prevalence, there was no si-nificant association between the presence of SLE and whether individuals had MetS or not(p¼0.117). Via a binary logistic regression, was evaluated the chance of specific factors associated with SLE predicting the presence of MetS. No significant association was detected between MetS and any SLE specific factors.
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Lemos et al. (2016) conducted a cross-sectional in Systemic lupus erythematosus (n=59). Systemic lupus erythematosus vs. Controls was evaluated on Metabolic syndrome (p=0.117). Systemic lupus erythematosus was associated with a 30.5% prevalence of metabolic syndrome compared to 20.5% in controls, which was not statistically significant (p=0.117).
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