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August 5, 2026CureusOpen Access

Prevalence and Associated Factors of Metabolic Syndrome in Patients With Systemic Lupus Erythematosus: A Cross-Sectional Study

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Authors

SGShehla GulHIHaider ImranYale New Haven HospitalRGRoheela GulKhyber Teaching Hospital

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Overview

Cross-sectional study determines prevalence of metabolic syndrome in systemic lupus erythematosus patients, indicating significant health implications.

Key Points

  • The study aimed to determine the prevalence of metabolic syndrome in patients with systemic lupus erythematosus and identify its associated factors.
  • Cross-sectional study conducted from January 2024 to December 2025
  • Sample included 427 adults diagnosed with SLE based on 2019 EULAR/ACR criteria
  • Multivariable logistic regression used to identify factors associated with metabolic syndrome.
  • 39.34% of patients with SLE met the diagnostic criteria for metabolic syndrome.
  • Factors associated with higher odds of metabolic syndrome included older age, obesity, longer disease duration, lupus nephritis, physical inactivity, family history of diabetes, and corticosteroid use.
  • Hydroxychloroquine use was associated with lower odds of metabolic syndrome.

Cite This Study

Gul et al. (2026) studied this question.

synapsesocial.com/papers/6a72e79c226790f370656dfehttps://doi.org/10.7759/cureus.113828
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Also Consider

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  1. 1Metabolic syndrome in patients with systemic lupus erythematosus from South India2015 · 4 citations
  2. 2Metabolic syndrome in systemic lupus erythematosus was closely related to body mass index, blood pressure, blood sugar, blood lipids, and arthritis2020 · 7 citations
  3. 3Associations of metabolic syndrome in SLE2020 · 30 citations
  4. 4Metabolic syndrome in patients with systemic lupus erythematosus: Association with disease activity, disease damage and age2018 · 18 citations
  5. 5Systemic Lupus Erythematosus (SLE) Therapy: The Old and the New2020 · 222 citations