Eight of 70 patients with systemic lupus erythematosus (SLE) followed for a median interval of 6 years and 8 months, developed malignancies. These included a case of reticulum‐cell sarcoma, multiple myeloma, Bowen's carcinoma of the skin and five carcinomas of the cervix. Six of the patients had been treated with corticosteroids, in 2 cases in association with azathioprine. An increased incidence of malignancy may be present in SLE and this possibility should be explored further.
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Canoso et al. (1974) studied this question.
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