Key result
Endovascular AAA repair was associated with significantly lower inflammatory markers (IL-6 p<0.002, TNF-alpha p<0.0004) and renal injury (ACR p<0.002) compared to conventional surgery.
Why the study?
Does endovascular AAA repair reduce inflammatory and renal injury responses compared to conventional surgery in patients with abdominal aortic aneurysms?
Population
43 patients (41 men; ages 58-81 years) with abdominal aortic aneurysms (AAAs)
Comparison
Endovascular AAA repair vs Conventional AAA surgery
Design
Cohort
Follow-up
perioperative period
Authors
Loading...
May favor endovascular AAA repair for lower inflammation; leaves open outcome benefits pending randomized confirmation.
Cohort (n=43)
Does endovascular AAA repair reduce inflammatory and renal injury responses compared to conventional surgery in patients with abdominal aortic aneurysms?
p-value: p=<0.002
Endovascular AAA repair is associated with significantly lower systemic inflammatory and renal injury responses compared to conventional open surgery.
Boyle et al. (2000) conducted a cohort in Abdominal aortic aneurysms (n=43). Endovascular AAA repair vs. Conventional aneurysm surgery was evaluated on Inflammatory and renal parameters (IL-6, TNF-alpha, ACR, urinary NAGs) (p=<0.002). Endovascular AAA repair was associated with significantly lower inflammatory markers (IL-6 p<0.002, TNF-alpha p<0.0004) and renal injury (ACR p<0.002) compared to conventional surgery.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: