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Two new pyrrolidine alkaloids called broussonetines C and D were isolated from the branch of Broussonetia kazinoki SIEB. (Moraceae). Broussonetines C and D were formulated as (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-(10-oxo-hydroxytridecyl)pyrrolidine (1) and (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-(9-oxo-13-hydroxytridecyl)pyrrolidine (2), respectively, by spectroscopic and chemical methods. 1 and 2 showed an inhibition to β-galactosidase and β-mannosidase.
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Shibano et al. (1997) studied this question.
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