Key result
This is a systematic review protocol designed to evaluate the effectiveness of Nissen fundoplication versus anterior and posterior partial fundoplications for GERD symptom control in adults.
Why the study?
Does Nissen fundoplication improve symptom control and reduce side effects compared to anterior and posterior partial fundoplications in adults with gastro-esophageal reflux disease?
Systematic Review
Does Nissen fundoplication improve symptom control and reduce side effects compared to anterior and posterior partial fundoplications in adults with gastro-esophageal reflux disease?
This is a protocol for a systematic review comparing Nissen fundoplication to partial fundoplications for GERD.
No immediate change to GERD surgical practice; leaves open comparative effectiveness of Nissen versus partial fundoplication.
REVIEW QUESTION/OBJECTIVE: The objective of this review is to determine the relative effectiveness of Nissen fundoplication compared to anterior and posterior partial fundoplication in controlling the symptoms of gastro-esophageal reflux disease and reducing their side effect profile in adults.The specific questions posed by this review are: what is the effectiveness of Nissen fundoplication in comparison to anterior partial fundoplication (90 degree, 120 degree and 180 degree) and posterior 270 degree fundoplication in terms of symptom control of gastro-esophageal reflux disease, and what are the side effects of these surgical interventions?
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Marshall‐Webb et al. (2018) conducted a systematic review in gastro-esophageal reflux disease. Nissen fundoplication vs. Anterior partial fundoplication (90, 120, and 180 degree) and posterior 270 degree fundoplication was evaluated on Symptom control of gastro-esophageal reflux disease and side effects. This is a systematic review protocol designed to evaluate the effectiveness of Nissen fundoplication versus anterior and posterior partial fundoplications for GERD symptom control in adults.
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