Key result
Polio survivors had significantly lower health-related quality of life compared to healthy controls (mean EQ-5D index 0.68 vs 0.94, p<0.001), with greater problems in mobility, usual activity, and anxiety/depression.
Cross-Sectional (n=362)
Yes
Polio survivors experience significantly reduced health-related quality of life, particularly in mobility and usual activities, compared to both healthy controls and individuals with non-polio related activity limitations.
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Suggests QoL monitoring for polio survivors; cross-sectional evidence leaves open prospective trials to inform care.
The purpose of this study is to assess health-related quality of life in polio survivors (PS) compared with that in the general population in Korea. Polio survivors (n = 120) from outpatient clinics at two hospitals, healthy controls (HC, n = 121) and members of the general population with activity limitations (AL, n = 121) recruited through a proportional-allocation, systematic sampling strategy from the Fourth Korean National Health and Nutrition Examination Survey were surveyed with self-rated health-related quality of life (Euro QoL five-dimensions). The proportion of participants who reported problems in mobility, usual activity, and symptoms of anxiety/depression were higher in the PS group compared with the HC and AL groups. There was no significant difference in the self-care dimension across the groups. Polio-specific questionnaire, pain, depression, fatigue, Modified Barthel Index (K-MBI) and Short Physical Performance Battery (SPPB) were assessed in the PS group. Those with post-poliomyelitis syndrome had greater problems in mobility, usual activity, and depression/anxiety. Polio survivors, especially those with more pain and fatigue symptoms, and those who did not have access to medical services had poorer health-related quality of life. These findings afford useful information for potential intervention improving quality of life in polio survivors.
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Yang et al. (2015) conducted a cross-sectional in Polio survivors (n=362). Polio survivorship vs. Healthy controls and general population with activity limitations was evaluated on Health-related quality of life (EQ-5D index score) (p=<0.001). Polio survivors had significantly lower health-related quality of life compared to healthy controls (mean EQ-5D index 0.68 vs 0.94, p<0.001), with greater problems in mobility, usual activity, and anxiety/depression.
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