Key result
Post-poliomyelitis syndrome was present in 77.2% of patients with a prior history of paralytic poliomyelitis, most commonly manifesting as joint pain, fatigue, and new weakness.
Cross-Sectional (n=167)
No
In a Brazilian tertiary care center, post-poliomyelitis syndrome is highly prevalent (77.2%) among patients with a history of paralytic poliomyelitis, presenting similarly to cohorts in other countries.
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Supports clinical awareness of post-poliomyelitis syndrome in polio survivors; leaves open generalizability beyond this single-center cross-sectional sample.
OBJECTIVE: To determine the frequency and clinical manifestations of patients with post-poliomyelitis syndrome (PPS) in a Brazilian division of neuromuscular disorders. METHODS: A total of 167 patients with prior history of paralytic poliomyelitis was investigated for PPS, based on international diagnostic criteria. Other variables analyzed were: gender, race, age at poliomyelitis infection, age at PPS onset, and PPS symptoms. RESULTS: One hundred and twenty-nine patients presented PPS, corresponding to 77.2% of the studied population. 62.8% were women and 37.2% were men. Mean age of patients with PPS at onset of PPS symptoms was 39.9±9.69 years. Their main clinical manifestations were: new weakness in the previously affected limbs (69%) and in the apparently not affected limbs (31%); joint pain (79.8%); fatigue (77.5%); muscle pain (76%); and cold intolerance (69.8%). CONCLUSIONS: Most patients of our sample presented PPS. In Brazil, PPS frequency and clinical features are quite similar to those of other countries.
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Quadros et al. (2012) conducted a cross-sectional in Post-poliomyelitis syndrome (n=167). Prior history of paralytic poliomyelitis was evaluated on Frequency of post-poliomyelitis syndrome (PPS). Post-poliomyelitis syndrome was present in 77.2% of patients with a prior history of paralytic poliomyelitis, most commonly manifesting as joint pain, fatigue, and new weakness.
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