Key result
Postpolio syndrome can occur in patients with a history of non-paralytic poliovirus infection, presenting with unilateral muscular atrophy and characteristic electromyography findings.
Case Report (n=1)
Postpolio syndrome should be considered in patients with unilateral muscular atrophy even when they have no history of paralytic poliomyelitis.
Supports considering postpolio syndrome in unexplained atrophy without paralytic history; hypothesis-generating pending larger studies.
A 73-year-old man presented with muscle weakness and atrophy of his right arm. Atrophy of his left brachia and left calf had occurred 13 years before without any improvement or deterioration. His sister and cousin had a history of paralytic poliomyelitis. Serum poliovirus type 2 neutralizing antibody was elevated to 128×. Electromyography revealed chronic denervation potentials not only in the muscles affected previously but also in the unaffected muscles. Acute and chronic denervation potentials were found in the newly affected muscle. Postpolio syndrome should be considered in patients with unilateral muscular atrophy even when they have no history of paralytic poliomyelitis.
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Maeda et al. (2022) conducted a case report in Postpolio syndrome (n=1). Non-paralytic poliovirus infection was evaluated on Diagnosis of postpolio syndrome based on clinical features, serology, and EMG findings. Postpolio syndrome can occur in patients with a history of non-paralytic poliovirus infection, presenting with unilateral muscular atrophy and characteristic electromyography findings.
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