Key result
Former polio sufferers reported significantly more muscular weakening and pain compared to matched controls, though controls also had considerable similar complaints, questioning the diagnosis validity.
Why the study?
Are self-reported symptoms of muscular weakening and pain specific to postpolio syndrome compared to matched controls?
Population
81 former polio sufferers and 116 gender and age matched controls
Design
Case-control
Authors
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Self-reported symptoms lack specificity for postpolio syndrome; challenges subjective diagnosis and leaves open need for objective criteria.
Case-Control (n=197)
Are self-reported symptoms of muscular weakening and pain specific to postpolio syndrome compared to matched controls?
The validity of diagnosing postpolio syndrome based solely on subjective symptoms without objective signs of denervation is questionable due to high background rates of similar complaints.
Aurlien et al. (2009) conducted a case-control in Postpolio syndrome (n=197). History of polio vs. Gender and age matched controls was evaluated on Self-reported muscular weakening and pain in different locations. Former polio sufferers reported significantly more muscular weakening and pain compared to matched controls, though controls also had considerable similar complaints, questioning the diagnosis validity.
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