Key result
Over a 4-year follow-up, individuals with post-polio syndrome experienced minor changes in disability, including a small but significant reduction in spontaneous walking speed (mean decrease 0.09 m/s) and specific muscle strength, with no change in overall perceived health.
Why the study?
What are the changes in disability over 4 years in a clinically based cohort of individuals with post-polio syndrome?
Population
106 individuals with poliomyelitis sequelae (post-polio syndrome) referred to a post-polio clinic
Design
Cohort
Follow-up
4 years
Authors
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Minimal 4-year disability progression supports conservative monitoring in post-polio syndrome; leaves open predictors of decline and longer-term outcomes.
Cohort (n=106)
No
What are the changes in disability over 4 years in a clinically based cohort of individuals with post-polio syndrome?
Mean Difference: 0.0925 (95% CI 0.0586–0.1264)
p-value: p=0.001
Individuals with post-polio syndrome showed only minor changes in disability and muscle strength over a 4-year follow-up period.
Willén et al. (2007) conducted a cohort in Post-polio syndrome (n=106). 4-year follow-up of post-polio syndrome vs. Baseline (initial assessment) was evaluated on Change in spontaneous walking speed (m/s) (MD 0.0925, 95% CI 0.0586-0.1264, p=0.001). Over a 4-year follow-up, individuals with post-polio syndrome experienced minor changes in disability, including a small but significant reduction in spontaneous walking speed (mean decrease 0.09 m/s) and specific muscle strength, with no change in overall perceived health.
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