Key result
Nonpharmaceutical interventions during the COVID-19 pandemic significantly decreased the positive rate of rotavirus (from 18.18% to 9.75%) and adenovirus (from 3.13% to 1.58%) in children with gastroenteritis.
Why the study?
Protective measures were adopted to impede COVID-19 transmission in China, but their effect on gastrointestinal infection in children remained to be investigated.
Do nonpharmaceutical interventions against COVID-19 reduce the spread of rotavirus and adenovirus in children with gastroenteritis?
Population
Outpatient children with gastroenteritis at Children's Hospital of Zhejiang University School of Medicine
Comparison
2020 pandemic period vs 2019 pre-pandemic period
Design
Retrospective observational study
Authors
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NPIs were associated with lower rotavirus and adenovirus rates in children; hypothesis-generating for targeted post-pandemic strategies.
Observational (n=42,789)
No
Do nonpharmaceutical interventions against COVID-19 reduce the spread of rotavirus and adenovirus in children with gastroenteritis?
Absolute Event Rate: 9.75% vs 18.18%
p-value: p=<0.001
Nonpharmaceutical interventions implemented during the COVID-19 pandemic were associated with a significant reduction in the transmission of rotavirus and adenovirus among children.
Zhang et al. (2022) conducted an observational in Gastroenteritis (n=42,789). Nonpharmaceutical interventions against COVID-19 vs. Pre-COVID-19 period (2019) was evaluated on Overall positive rate of rotavirus infection (p=<0.001). Nonpharmaceutical interventions during the COVID-19 pandemic significantly decreased the positive rate of rotavirus (from 18.18% to 9.75%) and adenovirus (from 3.13% to 1.58%) in children with gastroenteritis.
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