Elevated triglycerides may raise ischemic heart disease risk in obese females independent of fat distribution; hypothesis-generating, needs prospective validation.
Serum triglyceride levels were significantly raised in 37 markedly obese females, especially in the younger subjects; cholesterol and phospholipid levels were normal. Considerable variation in triglyceride levels of equally obese subjects was observed. No relationship was noted between triglyceride levels and the pattern of subcutaneous fat distribution. It is suggested that the high triglyceride levels of obese subjects may explain their predisposition to ischaemic heart disease.
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Rifkind et al. (1967) studied this question.
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