Intrapelvic Pressure and Urinary Flow Rate in Obstructed and Nonobstructed Human Kidneys

No AccessJournal of UrologyUrological Neurology and Urodynamics1 Jun 1982Intrapelvic Pressure and Urinary Flow Rate in Obstructed and Nonobstructed Human Kidneys C.-G. Bratt, M. Aurell, B.-E. Erlandson, A.E. Nilson, and S. Nilsson C.-G. BrattC.-G. Bratt , M. AurellM. Aurell , B.-E. ErlandsonB.-E. Erlandson , A.E. NilsonA.E. Nilson , and S. NilssonS. Nilsson View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54269-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The intrapelvic pressure and urinary flow rate were measured during rest and diuresis induced by intravenous infusion of mannitol solution or furosemide in 18 adult patients with unilateral hydronephrosis and in a control series of 4 patients without outflow obstruction. The findings were related to the renal parenchymal function of the kidney, evaluated by isotope renography, and the distal tubular function as shown by the maximum urine concentration ability. The resting pelvic pressure during normal hydration varied from 1.3 to 10cm. water in obstructed and nonobstructed kidneys. During osmotic diuresis the pressure gradually increased to an average maximum value of 34.5cm. water (range 15.0 to 137.0cm. water) in the hydronephrotic kidneys and 17.5cm. water (range 7.5 to 25.0cm. water) in the control kidneys, the difference being statistically significant. A statistically significant difference in maximum pressure during osmotic diuresis was found between hydronephrotic kidneys without (range 33.0 to 137.0cm. water) and with (range 15.0 to 24.0cm. water) previous episodes of upper urinary tract infections. In patients with hydronephrosis the maximum urinary flow rate was lower from the affected than from the nonobstructed contralateral kidney. In the control series the maximum flow rate during induced diuresis was never < 7ml. per minute, which probably is the highest inflow rate that could be used to demonstrate the presence of obstruction by measuring the intrapelvic pressure. The demonstration of intrapelvic pressures within normal limits in obstructed hydronephrotic kidneys with reduced maximum concentration ability after episodes of infection indicates that pressure measurements cannot be used to detect the presence of obstruction in complicated hydronephrosis. © 1982 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByFung L and Atala A (2018) CONSTANT ELEVATION IN RENAL PELVIC PRESSURE INDUCES AN INCREASE IN URINARY N-ACETYL-beta-D-GLUCOSAMINIDASE IN A NONOBSTRUCTIVE PORCINE MODELJournal of Urology, VOL. 159, NO. 1, (212-216), Online publication date: 1-Jan-1998.Fung L, Khoury A, McLorie G, Chait P and Churchill B (2018) Pressure Decay Half-life: A Method for Characterizing Upper Urinary Tract Urine TransportJournal of Urology, VOL. 155, NO. 3, (1045-1049), Online publication date: 1-Mar-1996.Palmer J and DiSandro M (2018) Diuretic Enhanced Duplex Doppler Sonography in 33 Children Presenting with Hydronephrosis: A Study of Test Sensitivity, Specificity and PrecisionJournal of Urology, VOL. 154, NO. 5, (1885-1888), Online publication date: 1-Nov-1995.Ordorica R, Lindfors K and Palmer J (2018) Diuretic Doppler Sonography Following Successful Repair of Renal Obstruction in ChildrenJournal of Urology, VOL. 150, NO. 2 Part 2, (774-777), Online publication date: 1-Aug-1993.Smyth T, Shortliffe L and Constantinou C (2018) The Effect of Urinary Flow and Bladder Fullness on Renal Pelvic Pressure in a Rat ModelJournal of Urology, VOL. 146, NO. 2 Part 2, (592-596), Online publication date: 1-Aug-1991.Kekomäki M and Vapaatalo H (2018) Renal Excretion of Prostanoids and Cyclic AMP in Chronic Partial Ureteral Obstruction of the RabbitJournal of Urology, VOL. 141, NO. 2, (395-397), Online publication date: 1-Feb-1989.Jones D, Holden D and George N (2018) Mechanism of Upper Tract Dilatation in Patients with Thick Walled Bladders, Chronic Retention of Urine and Associated HydroureteronephrosisJournal of Urology, VOL. 140, NO. 2, (326-329), Online publication date: 1-Aug-1988.Bratt C and Nilsson S (2018) Intrapelvic Pressure and Caliceal Dilatation in the Evaluation of Intermittent HydronephrosisJournal of Urology, VOL. 137, NO. 5, (845-848), Online publication date: 1-May-1987.Bratt C and Granerus G (2018) 125I-Hippuran Absorption from the Human Renal PelvisJournal of Urology, VOL. 136, NO. 3, (728-732), Online publication date: 1-Sep-1986.Tscholl R, Rehmann B, Stierli P and Locher J (2018) The Effects of Renal Pelvic Pressure Elevation on Isotope Nephrography and Renal Transit Time, an Experimental StudyJournal of Urology, VOL. 135, NO. 3, (629-633), Online publication date: 1-Mar-1986. Volume 127Issue 6June 1982Page: 1136-1142 Advertisement Copyright & Permissions© 1982 by The American Urological Association Education and Research, Inc.MetricsAuthor Information C.-G. Bratt More articles by this author M. Aurell More articles by this author B.-E. Erlandson More articles by this author A.E. Nilson More articles by this author S. Nilsson More articles by this author Expand All Advertisement Loading ...