Key result
Prolonged sigmoid acidosis (pHi < 7.10) predicted major morbidity after abdominal aortic surgery with 100% sensitivity and 92% specificity.
Why the study?
Does intramucosal pH monitoring predict major complications in patients undergoing abdominal aortic surgery?
Observational (n=34)
Open-label
Does intramucosal pH monitoring predict major complications in patients undergoing abdominal aortic surgery?
Sigmoid colon intramucosal pH monitoring is a highly sensitive and specific early predictor of major complications after abdominal aortic surgery.
Answers are grounded in this paper and cite their sources.
May support early risk stratification after aortic surgery; leaves open prospective validation before practice change.
The early detection and reversal of gastrointestinal ischaemia is thought to play a key role in minimizing the incidence of complications after abdominal aortic surgery. In an open prospective non-selective study intramucosal pH (pHi) was monitored in 27 patients undergoing elective aortic surgery and in seven submitted to emergency procedures. The pHi was monitored in the sigmoid colon in all 34 patients and in the stomach in 26. Eight patients developed major complications, four of whom had ischaemic colitis, and five died. Sigmoid acidosis (pHi below 7.10) served as an early warning; if acidosis was reversed within 2 h no major complication developed, if prolonged it was predictive of major morbidity (sensitivity 100 per cent, specificity 92 per cent). A colonic pHi below 6.86 predicted endoscopically detectable ischaemic colitis. A gastric pHi below 7.20 predicted major complications with a sensitivity of 100 per cent and specificity of 81 per cent. Both monitoring procedures were considered feasible, although monitoring in the sigmoid colon was found to be superior for the patients studied.
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Björck et al. (1994) conducted an observational in Abdominal aortic surgery (n=34). Sigmoid colon and gastric intramucosal pH monitoring was evaluated on Major complications. Prolonged sigmoid acidosis (pHi < 7.10) predicted major morbidity after abdominal aortic surgery with 100% sensitivity and 92% specificity.
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