Key result
Balloon dilation with simultaneous intrastent sonotherapy resulted in significant clinical improvement, decreased right ventricular pressure, and decreased Doppler velocity across stents at 3 months.
Why the study?
Does intrastent sonotherapy improve hemodynamics and clinical status in a pediatric patient with recurrent pulmonary vein restenosis?
Case Report (n=1)
Does intrastent sonotherapy improve hemodynamics and clinical status in a pediatric patient with recurrent pulmonary vein restenosis?
Intrastent sonotherapy combined with balloon dilation may be an effective treatment for severe neointimal proliferation and recurrent pulmonary vein restenosis in pediatric patients.
Answers are grounded in this paper and cite their sources.
May support intrastent sonotherapy for refractory pediatric pulmonary vein restenosis; hypothesis-generating and requires prospective validation.
A 2 year old boy developed recurrent pulmonary vein stenosis after surgical repair of infradiaphragmatic pulmonary venous connection. He had required implantation of stents in the left and right sided pulmonary veins at 7 and 13 months of age, respectively. By 2 years of age he had undergone three catheterisation procedures and two surgical procedures to treat recurrent pulmonary vein stenosis. His right ventricular pressure was suprasystemic and catheterisation showed severe neointimal proliferation of both left and right sided stents. At this time the stents were dilated by balloon with simultaneous intrastent sonotherapy. Three months later the patient's clinical improvement was significant, his right ventricular pressure had decreased, and Doppler velocity had decreased across both left and right sided stents.
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Colin J. McMahon (2003) conducted a case report in recurrent pulmonary vein stenosis (n=1). balloon dilation with simultaneous intrastent sonotherapy was evaluated on clinical improvement, right ventricular pressure, and Doppler velocity. Balloon dilation with simultaneous intrastent sonotherapy resulted in significant clinical improvement, decreased right ventricular pressure, and decreased Doppler velocity across stents at 3 months.
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