Precocious Puberty of Intracranial Origin

p RECOCIOUS puberty of intracranial origin has been the subject of exhaustive inquiry and numerous theories as to its causative mechanism have been advanced. The pineal region has been most frequently indicted in consideration of the production of this syndrome. Interest in this subject in the present instance was stimulated by a case of undoubted somatic and sexual precocity in which the lesion surgically exposed was an ectopic pineal tumor of the chiasmal region. The pertinent literature on ectopic pineal tumors and also that concerning precocity of intracranial origin has, therefore, been reviewed.