Key result
Patients with post-polio syndrome showed a significantly greater decrease in walking speed (14.1% vs 4.7%, p<0.05) and larger increases in leg tiredness and dyspnoea during the 6-minute walk test compared to healthy controls.
Why the study?
Do patients with post-polio syndrome exhibit different gait characteristics and fatigue levels during the 6-minute walk test compared to healthy controls?
Population
18 patients with post-polio syndrome (mean age 67, 50% male) and 11 healthy controls (mean age 68, 45% male).
Comparison
6-minute walk test combined with… vs Healthy controls undergoing the same 6MWT.
Design
Cross-sectional
Authors
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May warrant modified endurance testing protocols in post-polio syndrome; leaves open whether interventions mitigate fatigue and gait changes.
Cross-Sectional (n=29)
No
Do patients with post-polio syndrome exhibit different gait characteristics and fatigue levels during the 6-minute walk test compared to healthy controls?
Absolute Event Rate: 14.1% vs 4.7%
p-value: p=<0.05
The 6-minute walk test induces significant fatigue in post-polio syndrome patients, which is reflected in kinematic gait alterations such as increased hip flexion.
Vreede et al. (2013) conducted a cross-sectional in Post-polio syndrome (n=29). Post-polio syndrome vs. Healthy controls was evaluated on Decrease in walking speed from beginning to end of the 6-minute walk test (p=<0.05). Patients with post-polio syndrome showed a significantly greater decrease in walking speed (14.1% vs 4.7%, p<0.05) and larger increases in leg tiredness and dyspnoea during the 6-minute walk test compared to healthy controls.
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