Key result
Deployment of a Cordis AAA stent graft in a flow model slightly increased flow disturbances near the renal arteries compared to no stent graft, with no expected significant clinical implications.
Why the study?
Does the deployment of a AAA stent graft cause significant flow disturbances near the renal arteries in an in vitro aortic flow model?
Does the deployment of a AAA stent graft cause significant flow disturbances near the renal arteries in an in vitro aortic flow model?
In an in vitro model, AAA stent graft deployment caused only slight flow disturbances near the renal arteries, suggesting minimal clinical hemodynamic implications.
Answers are grounded in this paper and cite their sources.
Minimal renal flow disturbances after AAA stent deployment suggest no clinical action needed; leaves open in vivo hemodynamic validation.
The purpose of this study was to investigate the hemodynamic implications of a proximal shift in the aortic bifurcation that results from abdominal aortic aneurysm (AAA) stent graft deployment. A flow model was constructed in which an anatomically accurate model of the aorta was subjected to physiologic pulsatile flow. The model included the celiac, superior mesenteric, left and right renal arteries. The aortic bifurcation, leading to the right and left iliac arteries was included, as well as the lumbar curvature. Flow simulations were performed under resting and mild exercise conditions with and without a Cordis AAA stent graft deployed. Flow patterns were visualized with dye injection and recorded onto video. The flow rates through the iliac and renal arteries were continuously monitored using ultrasonic flowmeters. Flow visualization revealed that flow disturbances at the level of the renal arteries were slightly increased with the deployment of the stent graft. The orientation of the endolegs within the aorta had no perceptible effect on these disturbances. Under mild exercise conditions, very little flow disturbance was observed. In conclusion, there are slight changes in flow disturbance near the renal arteries due to stent graft deployment, but these changes would not be expected to have significant clinical implications.
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Walsh et al. (2003) studied Abdominal aortic aneurysm (AAA). Cordis AAA stent graft vs. Without stent graft was evaluated on Flow disturbances at the level of the renal arteries. Deployment of a Cordis AAA stent graft in a flow model slightly increased flow disturbances near the renal arteries compared to no stent graft, with no expected significant clinical implications.
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