Key result
The asymmetry in the diffusion term of nighttime heart rate variability was significantly decreased in hypertrophic cardiomyopathy patients compared to healthy subjects.
Observational (n=15)
Analysis of heart rate variability using Kramers-Moyal coefficients reveals decreased respiratory sinus arrhythmia in hypertrophic cardiomyopathy patients, offering a potential new quantitative diagnostic measure.
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May support HRV diffusion analysis in HCM detection; hypothesis-generating and requires validation before any clinical use.
Petelczyc et al. (2009) conducted an observational in Hypertrophic cardiomyopathy (n=15). Hypertrophic cardiomyopathy vs. Healthy subjects was evaluated on Asymmetry in the dependence of the diffusion term on the rescaled heart rate. The asymmetry in the diffusion term of nighttime heart rate variability was significantly decreased in hypertrophic cardiomyopathy patients compared to healthy subjects.
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