Key result
Intrathecal analgesic drug delivery successfully treated chronic, refractory pain in a patient with post-poliomyelitis syndrome, though skin complications required two pump relocations.
Why the study?
Does intrathecal analgesic drug delivery improve chronic, refractory pain in a patient with post-poliomyelitis syndrome?
Case Report (n=1)
Does intrathecal analgesic drug delivery improve chronic, refractory pain in a patient with post-poliomyelitis syndrome?
Intrathecal analgesic drug delivery may be an effective option for refractory pain in post-poliomyelitis syndrome, though skin complications at the pump site can be challenging.
May support use in refractory post-poliomyelitis pain; leaves open confirmation of efficacy and safety in controlled trials.
BACKGROUND Post-poliomyelitis syndrome (PPS) is a progressive neuromuscular syndrome, with chronic pain being one of the most prevalent symptoms. We present a case report on intrathecal analgesic drug delivery to diminish chro-nic, refractory pain in a patient with PPS. CASE REPORT In a wheelchair-bound 45-year-old female patient (Caucasian, body mass index [BMI] 20.5) with severe chronic, refractory pain, a Synchromed® II pump (Medtronic, Minneapolis, Minnesota, USA) was implanted after multidisciplinary consultation and a successful trial period. After 8 months, relocation of the pump due to regional pressure problems with surrounding erythema had to occur. A second pump relocation due to pressure pro-blems and skin erosion was needed 18 months after the first relocation, moving from the abdominal wall to the sheath of the rectus abdominis muscle, resulting in resolution of the problems. CONCLUSIONS In patients with PPS, intrathecal analgesic drug delivery can be an option to treat chronic, refractory pain. Multidisciplinary consultation is necessary to deal with the wide variety of problems in these patients. Skin problems at the site of the pump reservoir can be challenging and time-consuming and, ultimately, can necessitate relocation (or removal) of the device.
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Cornelis Wilhelmus Jacobus van Tilburg (2016) conducted a case report in Post-poliomyelitis syndrome (n=1). Intrathecal analgesic drug delivery was evaluated on Resolution of chronic, refractory pain and device complications. Intrathecal analgesic drug delivery successfully treated chronic, refractory pain in a patient with post-poliomyelitis syndrome, though skin complications required two pump relocations.
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