Key result
The 25-item post-polio quality of life scale (PP-QoL) demonstrated good fit to the Rasch model (p=0.156) and excellent test-retest reliability (ICC 0.916).
Cross-Sectional (n=271)
p-value: p=0.156
The newly developed 25-item PP-QoL scale is a reliable and valid disease-specific quality of life measure for patients with post-polio syndrome.
PP-QoL may aid post-polio QoL assessment; leaves open broader validation before clinical adoption.
OBJECTIVE: To design a disease-specific quality of life (QoL) questionnaire for people with post-polio syndrome (PPS). METHODS: Qualitative interviews were conducted with 45 people with PPS to identify themes and derive potential items reflecting impact upon QoL. After cognitive debriefing, these were made into a questionnaire pack along with comparative questionnaires and posted to 319 patients. The 271 (85%) returned questionnaires were subjected to exploratory factor analysis (EFA) and Rasch analysis. RESULTS: A 25 item scale, the post-polio quality of life scale (PP-QoL), showed good fit to the Rasch model (conditional chi-square p = 0.156), unidimensionality (% t-tests 2.0: CI 0.7-3.8), and Cronbach's alpha of 0.87. With the latent estimate transformed to a 0-100 scale, the mean score was 56.9 (SD 18.5) with only 3.3% of respondents at the floor or ceiling of the scale. Test-retest reliability showed an intraclass correlation coefficient (ICC) (2.1) of 0.916, and correlation of 0.85. CONCLUSION: The disease-specific PP-QoL demonstrated excellent reliability, appropriate concurrent validity, and satisfied the standards of the Rasch model. It enables examination of the impact of health status upon perceived QoL, and the impact of rehabilitation interventions. The scale is freely available for academic or not-for-profit users to improve research in this neglected, disabling condition. Implications for Rehabilitation In post-polio syndrome (PPS), existing work examines aspects of health-related quality of life (HRQoL), such as activity limitations. A disease-specific QoL measure would enable researchers to model the impact of health status, such as fatigue or mobility restrictions, upon QoL in PPS. The post-polio quality of life scale (PP-QoL) is based on the patients' lived experience, meets Rasch standards and is free for use for academic and not-for-profit researchers. The raw score is reliable for individual use in clinical settings, and interval scale transformation is available for parametric applications and the calculation of change scores.
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Quincey et al. (2016) conducted a cross-sectional in Post-polio syndrome (n=271). Post-polio quality of life scale (PP-QoL) was evaluated on Scale reliability and validity (Rasch model fit) (p=0.156). The 25-item post-polio quality of life scale (PP-QoL) demonstrated good fit to the Rasch model (p=0.156) and excellent test-retest reliability (ICC 0.916).
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