What question did this study set out to answer?

To assess the long-term cardiac disease risks associated with breast cancer radiation therapy in an expanding population of cancer survivors.

March 13, 2013New England Journal of Medicine

The Cardiovascular Perils of Cancer Survivorship

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Breast cancer survivorship and cardiac disease. Intervention: Radiation therapy.

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Key result

Older radiation techniques for breast cancer are associated with subsequent cardiac disease, though the exact risk remains unclear.

Population

Breast cancer survivors

Design

Editorial

Authors

JMJavid J. MoslehiCardio-Oncology

Discussion

Member takes

Implication

Discusses the cardiovascular risks associated with radiation therapy in breast cancer survivors.

Key Points

To assess the long-term cardiac disease risks associated with breast cancer radiation therapy in an expanding population of cancer survivors.
Reviewed historical and contemporary treatment paradigms combining breast-conserving surgery, mastectomy, and adjuvant radiation therapy.
Evaluated cardiovascular morbidity and survivorship data across evolving breast radiotherapy modalities.
Annual decreases in breast cancer mortality since 1990 resulted in an estimated 3 million cancer survivors in the United States by 2012.
Older breast radiation techniques show a clear association with subsequent cardiac disease, while cardiac risks from modern conformal approaches require ongoing evaluation.

Structured PICO

Population

Breast cancer survivors

Exposure

Radiation therapy

Discusses the cardiovascular risks associated with radiation therapy in breast cancer survivors.

Cite This Study

Javid J. Moslehi (2013) conducted an editorial in Breast cancer survivorship and cardiac disease. Radiation therapy was evaluated. Older radiation techniques for breast cancer are associated with subsequent cardiac disease, though the exact risk remains unclear.

synapsesocial.com/papers/6a9474aa6d20e72ae3707e62 https://doi.org/10.1056/nejme1215300

Topics

Women and heart disease

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The Cardiovascular Perils of Cancer Survivorship

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

The Cardiovascular Perils of Cancer Survivorship

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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