Pediatric severe sepsis and septic shock continue to be significant causes of childhood morbidity and mortality worldwide.The following review will highlight some of the controversies surrounding the consensus definitions.It will chronicle recent clinical and translational research, focusing on pediatric sepsis-specific challenges investigators face.It will also address the pathophysiology of severe sepsis and septic shock, including up-to-date therapeutic recommendations.
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John S. Giuliano (2013) studied this question.
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