Why the study?
Does the Sabin inactivated trivalent poliovirus vaccine elicit a humoral immune response in healthy adult males previously immunized in childhood?
Population
39 healthy adult males between the ages of 20 and 44 years with a history of childhood polio immunization
Design
Cohort
Follow-up
at least 18 months
Authors
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May support adult boosting strategies; hypothesis-generating for durability and generalizability beyond this small cohort.
Does the Sabin inactivated trivalent poliovirus vaccine elicit a humoral immune response in healthy adult males previously immunized in childhood?
The Sabin inactivated trivalent poliovirus vaccine safely and rapidly elicits a humoral immune response in adults, including those with waning immunity from childhood vaccination.
Murph et al. (1988) studied this question.
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