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HISTORY OF RESEARCH. Three considerations make it desirable to undertake a detailed study of the development of the corpus luteum of the guinea-pig. 1. Although a number of very careful investigations on the development of the corpus luteum have been published within the last ten years, there are a number of essential points about which different writers still disagree. It is not necessary to give a review of the literature on this subject, as this has been done repeatedly within recent years.1In regard to the development of the corpus luteum of the guinea-pig, there exists a short paper of Belloy,2who does not give distinct statements in regard to the age of the different corpora lutea which he describes. His results are in some important points opposed to the results obtained in other animals by different investigators. The most recent paper on the development of the corpus
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Leo Loeb (1906) studied this question.
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