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June 29, 2003Journal of Biological ChemistryOpen Access

Dentin Sialophosphoprotein Knockout Mouse Teeth Display Widened Predentin Zone and Develop Defective Dentin Mineralization Similar to Human Dentinogenesis Imperfecta Type III

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TSTaduru SreenathUniformed Services University of the Health SciencesTTTamizchelvi ThyagarajanNational Institutes of HealthBHBradford HallNational Institutes of Health

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Sreenath et al. (2003) studied this question.

synapsesocial.com/papers/6a9480ed258a5df809c52723https://doi.org/10.1074/jbc.m303908200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of Dentin Phosphophoryn Localization by Histochemical Stainings1986 · 49 citations
  2. 2Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ1988 · 675 citations
  3. 3Refined mapping of the human dentin sialophosphoprotein (DSPP) gene within the critical dentinogenesis imperfecta type II and dentin dysplasia type II loci1998 · 46 citations
  4. 4Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentine biomineralization2002 · 175 citations
  5. 5Genomic Organization, Chromosomal Mapping, and Promoter Analysis of the Mouse Dentin Sialophosphoprotein (Dspp) Gene, Which Codes for Both Dentin Sialoprotein and Dentin Phosphoprotein1998 · 214 citations