August 5, 1967BMJOpen Access

Heart block and coronary artery disease.

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Population

102 post-mortem hearts, comprising 14 cases of atrioventricular block associated with acute myocardial…

Design

Case-control

Authors

MDMichael J. DaviesSouth Australia Pathology DRD R RedwoodUniversity of North Carolina at Chapel Hill AHA HarrisSt. James's Hospital

Discussion

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Implication

Questions CAD primacy in chronic complete heart block; leaves open fibrosis predominance in modern cohorts.

Structured PICO

Population

102 post-mortem hearts, comprising 14 cases of atrioventricular (A-V) block associated with acute myocardial infarction, 53 cases of chronic complete heart block (average age at death 62), and a control series of 35 hearts from routine necropsy material (age >50 with normal ECG in the last 3 months of life).

Comparator

Control series of 35 hearts with normal ECG

Outcome

Pathological changes in the conduction system and coronary arteries to determine the etiology of complete heart block

This post-mortem study demonstrates that chronic complete heart block is predominantly caused by bilateral bundle-branch fibrosis rather than coronary artery disease.

Cite This Study

Davies et al. (1967) studied this question.

synapsesocial.com/papers/6a948159e4a5ef38ccbbe556 https://doi.org/10.1136/bmj.3.5561.342

Topics

Myocarditis Cardiomyopathy Cardiac amyloidosis Congenital heart disease adults

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Heart block and coronary artery disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Heart block and coronary artery disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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