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June 1, 1989The Journal of Experimental MedicineOpen Access

Phenotypic and functional alteration of CD4+ T cells after antigen stimulation. Resolution of two populations of memory T cells that both secrete interleukin 4.

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KHKyoko HayakawaFox Chase Cancer CenterRHRichard R. HardyUniversity of Utah

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Hayakawa et al. (1989) studied this question.

synapsesocial.com/papers/6a94828400cdb9bcecbbe692https://doi.org/10.1084/jem.169.6.2245
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.1986 · 7,554 citations
  2. 2Murine CD4+ T cell subsets defined.1988 · 104 citations
  3. 3Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.1987 · 1,041 citations
  4. 4Isolation of high-affinity memory B cells: phycoerythrin as a probe for antigen-binding cells.1987 · 129 citations
  5. 5Lymphokine production by murine T cells in the mixed leukocyte reaction.1988 · 27 citations