Key result
Cardiovascular reactivity patterns assessed via head-up tilt test identified disease-specific phenotypes, yielding sensitivities of 90.0-93.3% and specificities of 60.0-75.4% for CFS, syncope, and FMF.
Why the study?
Can specific cardiovascular reactivity patterns during a head-up tilt test differentiate between various clinical conditions?
Population
112 subjects including patients with chronic fatigue syndrome, non-CFS fatigue, neurally-mediated syncope…
Comparison
Shortened head-up tilt test measuring… vs Comparison across different disease groups and…
Design
Cross-sectional
Authors
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May differentiate CFS, syncope, and FMF phenotypes; leaves open prospective validation before clinical adoption.
Cross-Sectional (n=112)
Can specific cardiovascular reactivity patterns during a head-up tilt test differentiate between various clinical conditions?
Specific cardiovascular reactivity patterns during a head-up tilt test may help differentiate between clinical conditions such as chronic fatigue syndrome, neurally-mediated syncope, and familial Mediterranean fever.
Naschitz et al. (2004) conducted a cross-sectional in Chronic fatigue syndrome, neurally-mediated syncope, familial Mediterranean fever, psoriatic arthritis (n=112). Cardiovascular reactivity assessment via head-up tilt test vs. Healthy subjects and other clinical conditions was evaluated on Sensitivity and specificity of a linear discriminant score for disease-related phenotypes of cardiovascular reactivity. Cardiovascular reactivity patterns assessed via head-up tilt test identified disease-specific phenotypes, yielding sensitivities of 90.0-93.3% and specificities of 60.0-75.4% for CFS, syncope, and FMF.