Key result
High-risk pregnancies were associated with a significantly higher frequency of intrauterine structural heart defects compared to low-risk pregnancies (7.8% vs 2.7%, p<0.0001).
Why the study?
What is the frequency of intrauterine congenital heart defects in high-risk versus low-risk pregnancies?
Population
3,782 pregnant patients who underwent fetal echocardiography at a Pediatric Cardiology Unit
Comparison
High-risk pregnancy status for congenital heart… vs Low-risk pregnancy status
Design
Cross-sectional
Authors
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May inform selective fetal echocardiography in high-risk pregnancies; leaves open broader screening value pending prospective studies.
Observational (n=3,782)
No
What is the frequency of intrauterine congenital heart defects in high-risk versus low-risk pregnancies?
Absolute Event Rate: 7.8% vs 2.7%
p-value: p=<0.0001
Fetal echocardiography reveals a 7.8% prevalence of congenital heart defects in high-risk pregnancies and 2.7% in low-risk pregnancies, supporting its routine use in specific low-risk cases like multiple gestations or prior fetal death.
Özbarlas et al. (2011) conducted an observational in Congenital heart disease (n=3,782). High-risk pregnancy vs. Low-risk pregnancy was evaluated on Frequency of intrauterine structural heart defects (p=<0.0001). High-risk pregnancies were associated with a significantly higher frequency of intrauterine structural heart defects compared to low-risk pregnancies (7.8% vs 2.7%, p<0.0001).
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