Key result
Abnormal ductus arteriosus flow was highly sensitive (100%) and specific (95%) for predicting the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction.
Why the study?
Do prenatal echocardiographic markers predict the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction?
Population
52 fetuses with right ventricular outflow tract obstruction. Most common diagnosis was tetralogy of Fallot.
Comparison
Prenatal echocardiographic evaluation vs Comparison between fetuses that did and did not…
Design
Cohort
Follow-up
up to age < 30 days
Authors
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May support targeted neonatal preparedness in fetal RVOTO; leaves open prospective validation before changing practice.
Cohort (n=52)
Do prenatal echocardiographic markers predict the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction?
Abnormal ductus arteriosus flow on prenatal echocardiography is highly sensitive and specific for predicting the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction.
Quartermain et al. (2012) conducted a cohort in Right ventricular outflow tract obstruction (n=52). Prenatal echocardiographic markers (abnormal ductus arteriosus flow, low PV-Z-score, low PV/AoV ratio) vs. Normal echocardiographic parameters was evaluated on Need for neonatal intervention at age < 30 days. Abnormal ductus arteriosus flow was highly sensitive (100%) and specific (95%) for predicting the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction.
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