Key result
Severe pulmonary vein stenosis after AF catheter ablation can mimic pulmonary infection.
Case Report (n=1)
No
Pulmonary vein stenosis or occlusion should be considered in patients presenting with infection-like pulmonary symptoms after radiofrequency ablation for atrial fibrillation.
May warrant inclusion in the differential for post-ablation pulmonary symptoms; case reports leave open population-level risk and surveillance needs.
We report a case of severe pulmonary vein stenosis(PVS) with complete pulmonary vein occlusion(PVO) after radiofrequency ablation for atrial fibrillation(AF). A 51-year-old man presented to the respiratory department with chest tightness, dyspnea, and chest pain. Early chest computed tomography (CT) revealed inflammatory changes in the left lung and bilateral pleural effusions, and the patient responded poorly to antibiotic therapy. He had undergone radiofrequency catheter ablation for AF 5 months prior. On admission, inflammatory markers were not significantly elevated, procalcitonin was negative, and bronchoalveolar lavage fluid (BALF) culture and metagenomic next-generation sequencing (mNGS) revealed no definitive pathogenic infection. Subsequent cardiac CTA showed non-visualization of the left inferior pulmonary vein and stenosis of the left superior pulmonary vein near the left atrium, leading to a diagnosis of post-ablation pulmonary vein occlusion and stenosis. The patient underwent pulmonary vein stenting at another hospital, with follow-up CTA demonstrating restored opacification distal to the stents without intraluminal filling defects. This case highlights the need for prompt evaluation of pulmonary vein patency when focal pulmonary infection-like changes, chest pain, or pleural effusion occur after atrial fibrillation ablation when infection is not confirmed.
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Du et al. (2026) conducted a case report in Severe pulmonary vein stenosis and occlusion (n=1). Radiofrequency catheter ablation was evaluated on Development of pulmonary vein stenosis and occlusion. Radiofrequency catheter ablation for atrial fibrillation can lead to severe pulmonary vein stenosis and occlusion, which may present with infection-like pulmonary findings and require prompt evaluation.
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