Key result
Over an 8-year follow-up, individuals with late polio experienced a 9-15% decrease in muscle strength, decreased endurance, and evidence of ongoing denervation/reinnervation.
Cohort (n=21)
In individuals with late polio, there is a progressive decline in muscle strength and endurance over 8 years, accompanied by signs of ongoing denervation and reinnervation.
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Supports monitoring for progressive weakness in late polio; leaves open whether interventions can modify decline.
Grimby et al. (1998) conducted a cohort in Late polio (n=21). Late polio was evaluated on Muscle strength, muscle fiber size, and dynamic electromyogram. Over an 8-year follow-up, individuals with late polio experienced a 9-15% decrease in muscle strength, decreased endurance, and evidence of ongoing denervation/reinnervation.
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