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We report here an operationally simple copper‐catalysed synthesis of imidazo[1,2‐a]pyridines through CH activation with oxidative linkage of two CN bonds under very mild conditions using molecular oxygen as a sole oxidant. The process allows the quick assembly of imidazo[1,2‐a]pyridines including the antiulcer drug zolimidine from inexpensive and readily available 2‐aminopyridines and methyl ketones with broad range of functional group tolerance. magnified image
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Mohan et al. (2013) studied this question.
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