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Purpose : This study investigated the effects of osteoarthritis therapy using images and histological diagnosis after microcurrents were applied to osteoarthritic rats. Methods : Osteoarthritis was induced with a mixture of 2% carrageenan and 2% kaolin. The mixture (0.1 m ) was injected into the knee joints of rats. Osteoarthritis with articulation received microcurrent stimulation for four weeks (15 min/day, 5 days/week): treated with pulsation frequency of 5 pps and a stimulation intensity of 25 μA . Results : Osteoarthritis of the control group constantly changed. The group with a stimulation intensity of 25 μA applied to the surface of the articular cartilage experienced near normal recovery according to image diagnosis. The result of histological and immunohistochemistry inspection confirms that microcurrent stimulation had a positive effect on the treatment of osteoarthritis. Conclusion : The differences among images and histological diagnoses show that steoarthritis will experience constant progression from stimulation.
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Jin et al. (2011) studied this question.
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